Ziglip-M Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Warnings Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Metformin HCl 1,000 mg, sitagliptin phosphate monohydrate 64.25 mg (equiv to sitagliptin 50 mg)

Indications/Uses

Type 2 DM.

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Dosage/Direction for Use

1 tab/day. Individualized to max sitagliptin 100 mg & metformin 2,000 mg.

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Overdosage

View Ziglip-M overdosage for action to be taken in the event of an overdose.

Administration

Should be taken with food.

Contraindications

Diabetic ketoacidosis, diabetic pre-coma; moderate & severe renal impairment (CrCl <60 mL/min). Acute conditions potentially alter renal function (eg, dehydration, severe infection, shock, IV iodinated contrasts). Acute or chronic disease may cause tissue hypoxia (eg, cardiac or respiratory failure). Hepatic impairment; acute alcohol intoxication, alcoholism. Lactation.

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Warnings

For additional cautionary notes to warn of the potential risk of using the medicine... Click to view Ziglip-M detailed prescribing information

Special Precautions

Patients w/ Type 1 DM or for diabetic ketoacidosis. Determine serum CrCl regularly; increased incidence of metformin-related lactic acidosis w/ degree of renal impairment. Potential risk for hypoglycaemia w/ sulphonylurea or insulin combination. Pancreatitis. Pregnancy.

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Use In Pregnancy & Lactation

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Drug Interactions

Minimal effect on plasma digoxin conc w/ sitagliptin.

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Storage

View Ziglip-M storage conditions for details to ensure optimal shelf-life.

Description

View Ziglip-M description for details of the chemical structure and excipients (inactive components).

Action

View Ziglip-M mechanism of action for pharmacodynamics and pharmacokinetics details.

MIMS Class

Antidiabetic Agents

ATC Classification

A10BD07 - metformin and sitagliptin ; Belongs to the class of combinations of oral blood glucose lowering drugs. Used in the treatment of diabetes.

Regulatory Classification

POM

Presentation/Packing

Form

Ziglip-M FC tab

Packing/Price

1 × 10's;10 × 10's;100's;3 × 10's;30's

Ziglip-M

metformin + sitagliptin

Manufacturer:

Zifam Pinnacle

Distributor:

Pinnacle House