Pacific Pharma


AA Medical
Concise Prescribing Info
Sepsis; meningitis; abdominal infections (peritonitis, biliary infections & GIT); bones, joints, soft tissue & skin, wound infection; perioperative prophylaxis of infections; infections in patients w/ impaired defense mechanism; renal infections & UTI, resp tract infection (pneumonia, ENT infections), gonorrhea.
Dosage/Direction for Use
IM/IV Adult & childn >12 yr 1-2 g inj once daily. Severe cases or infections caused by moderately sensitive organisms Increase to 4 g once daily. Infant & childn (3 wk-12 yr) 20-80 mg/kg daily. Weighing ≥50 kg ≥50 mg/kg as a slow IV infusion at least 30 min. Neonates ≤2 wk 20-50 mg/kg daily. Max: 50 mg/kg. Meningitis 100 mg/kg once daily. Max: 4 g daily. Duration of therapy: Neisseria meningitidis: 4 days; H. influenzae: 6 days; Strep pneumonia: 7 days; Susceptible enterobacteriaceae: 10-14 days. Gonorrhea 250 mg IM single dose. Pre-op prophylaxis 1-2 g single dose 30-90 min prior to surgery.  Preterminal renal failure (CrCl <10 mL/min) Max: 2 g daily.
Hypersensitivity to cephalosporins & penicillins. Pregnancy (1st trimester).
Special Precautions
Patients w/ history of hypersensitivity reactions to other drugs. Penicillin-sensitive patients. Discontinue use upon detection of sludge in the gallbladder by sonograms. Blood cell count should be check regularly during prolonged treatment. Hyperbilirubinemic neonates, especially prematures.
Adverse Reactions
Diarrhea, nausea, vomiting, stomatitis, glossitis. Eosinophilia, leucopenia, granulocytopenia, hemolytic anemia, thrombocytopenia. Exanthema, allergic dermatitis, pruritus, urticaria, edema, erythema multiforme.
MIMS Class
ATC Classification
J01DD04 - ceftriaxone ; Belongs to the class of third-generation cephalosporins. Used in the systemic treatment of infections.
Traxone inj 1 g
(+ 10 mL water for inj (amp)) 1's
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