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Due to the mechanism of action of angiotensin II antagonists, a risk for the fetus can not be excluded. In utero exposure to ACE inhibitors given to pregnant women during the 2nd and 3rd trimesters has been reported to cause injury and death to the developing fetus. As for any drug that also acts directly on the renin-angiotensin-aldosterone system, Tensar should not be used during pregnancy. If pregnancy is detected during therapy, Tensar should be discontinued as soon as possible.
It is not known whether Tensar is excreted in human milk. Valsartan was excreted in the milk of lactating rats. Thus it is not advisable to use Tensar in lactating mothers.
