Pacsartan-I Dosage/Direction for Use

Essential Hypertension: The usual recommended initial and maintenance dose is 150 mg once daily, with or without food. In patients insufficiently controlled with 150 mg once daily, the dose of Irbesartan can be increased to 300 mg or other antihypertensive agents can be added.
Irbesartan at a dose of 150 mg once daily generally provides a better 24 hour blood pressure control than 75 mg. However, initiation of therapy with 75 mg could be considered, particularly in haemodialysed patients and in the elderly over 75 years.
In particular, the addition of a diuretic such as hydrochlorothiazide has been shown to have an additive effect with this drug.
Treatment of renal disease in adult patients with hypertension and type 2 diabetes mellitus: In hypertensive type 2 diabetic patients, therapy should be initiated at 150 mg Irbesartan once daily and titrated up to 300 mg once daily as the preferred maintenance dose for treatment of renal disease. The demonstration of renal benefit of Irbesartan in hypertensive type 2 diabetic patients in base on studies where Irbesartan was used in addition to other antihypertensive agents, as needed, to reach target blood pressure.
Renal impairment: No dosage adjustment is necessary in patients with impaired renal function. A lower starting dose (75 mg) should be considered for patients undergoing haemodialysis.
Elderly patients: Although consideration should be given to initiating therapy with 75 mg in patients over 75 years of age, dosage adjustment is not usually necessary for the elderly.
If Pacsartan-I was taken more than a patient should, accidently, contact a doctor immediately.
If missed to take a daily dose of Pacsartan-I accidently, just take the next dose as normal. Do not take a double dose to make up for a forgotten dose.