Ixazomib is used together with other medicines to treat a type of blood cancer called “multiple myeloma”.
Take Ixazomib exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Take it on an empty stomach, at least 1 hour before or 2 hours after a meal. Swallow it whole. Do not break or chew the capsule. Try to take it at the time each day.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the course of your treatment depending on your response to this medicine.
Ixazomib must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Do not take this medicine if you are breastfeeding.
Inform your doctor if you have kidney or liver disease.
Let your doctor know if you are pregnant.
For as long as you are taking this medicine, you may need to have regular blood tests to check your body’s response to the medicine. Your doctor will advise you about how often you need to have blood tests.
Ixazomib may cause any of the following side effects: diarrhoea, constipation, nausea, vomiting, swelling of the ankles, feet or hand, and rash.
This medicine may make you drowsy or dizzy. If affected, do not drive or take part in any activity in which you need to be alert.
Ixazomib will cause the level of your white blood cells and platelets to drop.
White blood cells help your body to fight infections. A fall in the level of your white blood cells may put you at higher risk for infections, such as coughs, colds and flu, which may lead to more serious infections. Avoid crowded places and people who are sick. Alert your doctor if you have a fever, or a cough or flu that does not go away.
Platelets help your blood to clot when there is a cut in the skin. A fall in the level of your platelets may put you at risk of bleeding more than usual. Do not take part in activities where you may fall or get injured, such as contact sports. Alert your doctor if you get any unusual bruising (large bruises or several bruises, especially if the bruises appeared on their own) or bleeding that takes a long time to stop (for example, too much bleeding when you floss or brush your teeth).
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking any of these medicines:
- medicines for TB e.g. rifampicin
- medicines for epilepsy (fits or seizure) e.g. phenytoin, carbamazepine
- St. John’s wort (herbal medicine)
This list does not include all medicines that may interact with Ixazomib.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Avoid alcohol.
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.