Fertility: No human studies of the effects of Clotrimazole on fertility have been performed, however, animal studies have not demonstrated any effects of the drug on fertility.
Pregnancy: There are limited amount of data from the use of Clotrimazole in pregnant women. Animal studies do not indicate direct or indirect harmful effects with respect to reproductive toxicity. As a precautionary measure, it is preferable to avoid the use of Clotrimazole during the first trimester of pregnancy.
Lactation: Available pharmacodynamic/toxicological data in animals have shown excretion of Clotrimazole / metabolites in milk. Breast-feeding should be discontinued during treatment with Clotrimazole.