Generic Medicine Info
Indications and Dosage
Adult: As 10% cream/lotion: Apply a thin layer uniformly and massage thoroughly onto the whole body from neck to toes after bathing and drying. Repeat application once daily, preferably in the evening, for a total of 3-5 days.
Child: <3 yr Apply once daily w/ medical supervision; ≥3 yr Same as adult dose.

Pruritic skin disorders
Adult: As 10% cream/lotion: Apply gently onto affected area(s) bid or tid.
Child: <3 yr Apply once daily w/ medical supervision; ≥3 yr Same as adult dose.
Hypersensitivity. Acute exudative dermatoses.
Special Precautions
Childn. Pregnancy and lactation.
Adverse Reactions
Significant: Local hypersensitivity reaction and irritation.
Nervous: Localised warm feeling.
Dermatologic: Contact dermatitis, pruritus, rash.
Patient Counseling Information
Avoid application to the face, eyes, mouth, or on acutely inflamed, denuded, or weeping skin.
Description: Crotamiton is an acaricide agent that acts on the motor system of mites (e.g. Sarcoptes scabiei) through irreversible cessation of spontaneous movements. Additionally, it has antipruritic effects through inhibition of histamine, serotonin, and PAR-2.
Onset: Antipruritic effects: 6-10 hr.
Absorption: Rapidly penetrates into the skin; systemically absorbed. Time to peak plasma concentration: 4-10 hr.
Excretion: Via urine (4.8-8.8%).
Chemical Structure

Chemical Structure Image

Source: National Center for Biotechnology Information. PubChem Database. Crotamiton, CID=688020, (accessed on Jan. 22, 2020)

Store below 25°C.
MIMS Class
Topical Antifungals & Antiparasites
Anon. Crotamiton. Lexicomp Online. Hudson, Ohio. Wolters Kluwer Clinical Drug Information, Inc. Accessed 06/07/2017.

Buckingham R (ed). Crotamiton. Martindale: The Complete Drug Reference [online]. London. Pharmaceutical Press. Accessed 06/07/2017.

Eurax Cream; Lotion (Ranbaxy Laboratories Inc.). DailyMed. Source: U.S. National Library of Medicine. Accessed 06/07/2017.

Joint Formulary Committee. Crotamiton. British National Formulary [online]. London. BMJ Group and Pharmaceutical Press. Accessed 06/07/2017.

McEvoy GK, Snow EK, Miller J et al (eds). Crotamiton (Topical). AHFS Drug Information (AHFS DI) [online]. American Society of Health-System Pharmacists (ASHP). Accessed 06/07/2017.

Disclaimer: This information is independently developed by MIMS based on Crotamiton from various references and is provided for your reference only. Therapeutic uses, prescribing information and product availability may vary between countries. Please refer to MIMS Product Monographs for specific and locally approved prescribing information. Although great effort has been made to ensure content accuracy, MIMS shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2022 MIMS. All rights reserved. Powered by
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