Anaphylaxis & angioedema. Discontinue use if psychiatric & paradoxical reactions occur. Not recommended as primary treatment of psychotic illness; not to be used alone for treatment of depression or anxiety-associated depression. Severely depressed or suicidal patients. Complex sleep-related behaviors; chronic resp insufficiency. History of alcohol or drug abuse. May develop tolerance, dependence, rebound insomnia & anxiety; induce anterograde amnesia. Avoid abrupt w/drawal. Not for long-term use. Combination w/ CNS depressants, alcohol. May affect ability to drive & use machines. Not to be used in severe hepatic insufficiency. Women of childbearing potential. Avoid use during pregnancy. Not be used during lactation. Not recommended in childn <18 yr. Elderly.
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