Adult Cryptococcal meningitis & infections at other sites 400 mg on 1st day followed by 200-400 mg once daily. Duration of treatment for cryptococcal meningitis for 6-8 wk.
Prevention of cryptococcal meningitis relapse in patient w/ AIDS 200 mg daily after receiving full course of primary therapy.
Candidemia, disseminated candidiasis & other invasive candidal infections 400 mg on 1st day followed by 200 mg daily, may be increased to 400 mg daily.
Oropharyngeal candidiasis 50 mg once daily for 7-14 days.
Atrophic oral candidiasis associated w/ dentures 50 mg once daily for 14 days concurrently w/ local antiseptic.
Other mucosal candidal infections (except vag candidiasis) 50-100 mg daily for 14-30 days.
Prevention of oropharyngeal candidiasis relapse in patient w/ AIDS 150 mg once wkly after receiving full course of primary therapy.
Vag candidiasis, candida balanitis 150 mg as single oral dose.
Reduce incidence of recurrent vag candidiasis 150 mg once mthly for 4-12 mth.
Prevention of candidiasis 50-400 mg once daily.
Dermal infections eg, tinea pedis, corporis & cruris & candida infections 150 mg once wkly or 50 mg once daily for 2-4 wk.
Tinea pedis Up to 6 wk.
Tinea versicolor 300 mg once wkly for 2 wk or 300-400 mg single dose or 50 mg once daily for 2-4 wk.
Patient w/ high risk of systemic infection 400 mg once daily.
Renal impairment Initial loading dose: 50-400 mg.