Adult Herpes simplex infection 200 mg (400 mg in immunocompromised patient) 5 times daily for 5 days.
Prevention of recurrent herpes simplex infection 200 mg qds or 400 mg bd, reduced to 200 mg bd-tds when indicated. Periodically interrupt therapy at 6-12 mth to observe possible changes in nature of disease.
Prophylaxis of herpes simplex infection in immunocompromised patient 200 mg qds at 6-hr intervals.
Severely immunocompromised patient Dose may be doubled to 400 mg.
Varicella & herpes zoster infection 800 mg 5 times daily for 7 days.
Paed Herpes simplex infection & prophylaxis of herpes simplex infection in immunocompromised Childn ≥2 yr Adult dose;
<2 yr ½ adult dose.
Varicella infection Childn >6 yr 800 mg qds;
2-6 yr 400 mg qds;
<2 yr 200 mg qds. Dosing may be calculated as 20 mg/kg (max 800 mg) qds. Continue treatment for 5 days.
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