Patients with: Untreated cardiac failure; Cardiogenic shock; Sinoatrial block; Second or third degree AV block; Marked bradycardia; Severe asthma; Sick sinus syndrome; Hypotension; Severe peripheral circulatory disturbances; Hypersensitivity to bisoprolol in Vasoten; Untreated tumours of the adrenal gland (phaeochromocytoma); Metabolic acidosis.