Varivax

Varivax

vaccine, varicella-zoster

Manufacturer:

Merck Sharp & Dohme

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Live attenuated varicella virus (Oka/Merck strain)
Indications/Uses
Vaccination against varicella in individuals ≥12 mth.
Dosage/Direction for Use
Adult & adolescent ≥13 yr Two 0.5-mL SC inj 4-8 wk apart. Childn 12 mth-12 yr 0.5-mL SC inj as single dose. Min interval of 3 mth between doses if 2nd dose is administered.
Contraindications
Hypersensitivity to vaccine including gelatin; neomycin. Blood dyscrasias, leukemia, lymphoma or other malignant neoplasms affecting bone marrow or lymphatic system. Immunosuppressive therapy eg, high-dose corticosteroids. Primary & acquired immunodeficiency states. Family history of congenital or hereditary immunodeficiency. Active untreated TB; active febrile resp illness w/ fever >38.5°C. Avoid pregnancy for 3 mth following vaccination.
Special Precautions
Not to be inj IV. HIV-infected w/ or w/o immunosuppression. Avoid close association w/ high-risk individuals eg, immunocompromised, pregnant women & newborn infants w/o documented +ve history of varicella or lab evidence of prior infection for up to 6 wk following vaccination. Avoid pregnancy for 3 mth after vaccination in women of childbearing potential. Not to be used during pregnancy. Lactation. Childn <1 yr. Not recommended in infant <12 mth.
Adverse Reactions
Upper & lower resp illness, cough, irritability, fatigue, disturbed sleep, diarrhea, loss of appetite, vomiting, otitis, headache, malaise, abdominal pain, other rash, nausea, chills, lymphadenopathy, myalgia, allergic reactions (including allergic rash & hives), stiff neck, arthralgia, itching.
Drug Interactions
Reye syndrome w/ salicylates; avoid use 6 wk after vaccination. Defer vaccination at least 5 mth following Ig or varicella-zoster Ig administration, or blood or plasma transfusions.
MIMS Class
Vaccines, Antisera & Immunologicals
ATC Classification
J07BK01 - varicella, live attenuated ; Belongs to the class of varicella viral vaccines.
Presentation/Packing
Form
Varivax vaccine (inj) (lyo, vial) 0.5 mL
Packing/Price
(+ diluent) 1's
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