100 mg Patient ≥16 yr 100 mg once daily.
150 mg Adult & adolescent at least 30 kg 150 mg bd or 300 mg once daily.
CrCl 30 to <50 mL/min Initially 150 mg. Maintenance: 150 mg once daily,
15 to <30 mL/min Initially 150 mg. Maintenance: 100 mg once daily,
5 to <15 mL/min Initially 150 mg. Maintenance: 50 mg once daily,
<5 mL/min Initially 50 mg. Maintenance: 25 mg once daily.
Childn >3 mth, 21-30 kg 75 mg in the morning & 150 mg in the evening,
14-21 kg 75 mg bd.
Childn >3 mth, <30 kg & CrCl 30 to <50 mL/min Initially 4 mg/kg. Maintenance: 4 mg/kg once daily,
15 to <30 mL/min Initially 4 mg/kg. Maintenance: 2.6 mg/kg once daily,
5 to <15 mL/min Initially 4 mg/kg. Maintenance: 1.3 mg/kg once daily,
<5 mL/min Initially 1.3 mg/kg. Maintenance: 0.7 mg/kg once daily.
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