Tigecycline is an antibiotic. It is used to treat certain bacterial infections of the lungs, skin, and abdomen (belly).
Tigecycline may be used to treat other conditions as decided by your doctor.
Tigecycline injection is to be given intravenously (into the vein). It is delivered directly into the bloodstream via the blood vessel.
Your doctor or nurse will administer the injection for you.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your infection and your response to the medication.
You must complete the entire course of this medicine. If you don’t, the infection will not be properly controlled.
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Tigecycline.
If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
Do not use Tigecycline if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to this medicine or similar antibiotics such as tetracycline.
Inform your doctor if you have the following conditions:
- liver disease
- diabetic foot infection
Let your doctor know if you are pregnant or breastfeeding.
Why is it important to keep my appointments with the doctor?
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
- Routine tests (e.g. liver function, blood clotting time) may be done while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
- Regular monitoring of signs and symptoms of allergic reactions may also be needed.
Tigecycline may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.
Other side effects include any of the following: indigestion, loss of appetite, and pain or swelling at the injection site.
This medicine may also make your skin more sensitive to sunlight. Apply sunscreen when going outdoors and avoid prolonged exposure to sunlight and UV lamps.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- rashes, breathlessness, swelling of the face, eyes or mouth
- yellowing of the skin or eyes, abdominal pain, dark coloured urine, tiredness, swelling in the legs and ankles
- severe abdominal pain, nausea and vomiting
- severe or bloody diarrhoea, stomach pain or cramps, fever
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking warfarin (blood-thinning medicine).
Inform your doctor if you are currently taking birth control pills as Tigecycline can reduce its effectiveness. You should not stop or start any birth control pills without first informing your doctor. Ask your doctor about using non-hormonal birth control as an alternative while being treated with this medicine.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
Avoid alcohol.
Store unopened vials in a cool, dry place away from the reach of children.
Reconstituted solution may be stored at room temperature for up to 24 hours or refrigerated for up to 48 hours.
Medicines must not be used past the expiry date.
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