Cap Adult Serious infections 150-300 mg 6 hrly.
More severe infections 300-450 mg 6 hrly.
Childn Serious infections 8-16 mg/kg daily in 3-4 divided doses.
More severe infections 16-20 mg/kg daily in 3-4 divided doses.
Pneumocystis jiroveci pneumonia in patient w/ AIDS 300-450 mg orally every 6 hr + primaquine 15-30 mg once daily for 21 days.
Inj Adult Intra-abdominal area, female pelvis & other complicated or serious infections 2,400-2,700 mg in 2, 3 or 4 equal doses.
Less complicated infections 1,200-1,800 mg daily in 3 or 4 equal doses. Max: 4,800 mg daily or single dose 600 mg IM.
Childn >1 mth 20-40 mg/kg daily in 3 or 4 equal doses.
Neonate <1 mth 15-20 mg/kg daily in 3 or 4 equal doses.
Small premature infant 15 mg/kg daily in 3 or 4 equal doses.
β-hemolytic Streptococcal infections Continue treatment for at least 10 days.
Inpatient treatment of pelvic inflammatory disease 900 mg IV every 8 hr + gentamicin 2 mg/kg followed by 1.5 mg/kg every 8 hr for at least 4 days & at least 48 hr after improvement.
Toxoplasmic encephalitis in patient w/ AIDS 600-1,200 mg every 6 hr for 2 wk followed by 300-600 mg orally every 6 hr. Total duration: 8-10 wk.
Pneumocystis jiroveci pneumonia in patient w/ AIDS 600-900 mg every 6 hr or 900 mg every 8 hr.
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