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Oxytetracycline with Polymyxin B ophthalmic preparations are administered as a small quantity (approximately 1 cm) of the ointment. The preparation should be instilled or applied into the conjunctival sac of the lower lid 4 to 6 times daily until the infection is cleared and healing is complete. This may take from one day to several weeks depending on the nature and severity of the infection. In blepharitis, scales and crusts should be removed before applying medication. For prophylaxis, the same procedure is followed on the day before the operation and subsequently for several days following it.
The patient should be instructed to avoid contamination of the tip of the tube when applying the ointment.
