Tepotinib is used to treat a certain cancer of the lungs called non-small cell lung cancer in individuals with abnormal changes in their genes called MET.
It is used for those whose tumour has spread to other parts of the body.
Take Tepotinib exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
Take it together with food or immediately after a meal. Try to take it at the same time each day.
Swallow the tablet whole with a glass of water. Do not chew, crush, or break the tablet.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the type and severity of your condition.
Take the missed dose as soon as you remember. If it is less than or equal to 8 hours before the next dose is due, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Do not take this medicine if you are pregnant. If you become pregnant while on Tepotinib therapy, alert your doctor immediately. This medicine may cause harm to your unborn child.
It is important that you do not get pregnant while taking this medicine. You must use proven birth control methods during Tepotinib therapy and for 1 week after stopping the treatment.
Men with partners of childbearing potential must use proven birth control methods during Tepotinib therapy and for 1 week after stopping the treatment. You may wish to discuss other reliable methods of birth control with your doctor.
Do not breastfeed while you are being treated with this medicine.
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
- Certain tests to confirm if you have changes in your MET gene must be done to know if this medicine is suited for you to take.
- Pregnancy tests must also be done before you start your treatment with this medicine.
- Routine tests (e.g. liver or kidney function, electrolyte levels, and complete blood count) may be done while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
- Regular monitoring of signs of lung diseases or breathing problems may also be needed.
Tepotinib may cause any of the following side effects: nausea, vomiting, diarrhoea, stomach pain, constipation, tiredness, and muscle pain.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- fever, cough, shortness of breath, or other new or worsening breathing problems
- yellowing of the skin or eyes, abdominal pain, dark coloured urine, tiredness, swelling in the legs and ankles
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Inform your doctor and pharmacist if you are taking any of these medicines:
- medicines for fits or seizures e.g. carbamazepine, phenytoin
- rifampicin (medicine for TB, a lung infection known as tuberculosis)
- itraconazole (medicine for fungal infection)
- digoxin (medicine for heart disease)
- metformin (medicine for diabetes)
- St. John's wort (herbal medicine)
This list does not include all medicines that may interact with Tepotinib.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
Avoid alcohol.
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.
Protect from moisture.
As Tepotinib is a cancer medicine, always return any unused medicine to the clinic, hospital or pharmacy for disposal. Do not throw it away in the household waste.
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