At therapeutic doses, cetirizine does not potentiate the effect of alcohol (at blood level of 0.8 g/L). Care should, however, be taken.
Activities Requiring Mental Alertness: In clinical trials the occurrence of somnolence has been reported in some patients taking cetirizine. Due caution should therefore be exercised when driving a car or operating potentially dangerous machinery. Patient should be advised, however, to take care not to exceed the recommended dose.