Romiplostim is used to treat long-term cases of idiopathic thrombocytopenic purpura (blood disorder caused by a decreased number of platelets leading to excessive bleeding, easy bruising and multiple tiny red or purplish spots on the skin or the insides of the mouth) when other treatments or surgery to remove the spleen have not worked sufficiently.
Romiplostim may be used to treat other conditions as decided by your doctor.
Romiplostim is to be injected subcutaneously (into the fatty layer under the skin, usually in the thigh, upper arm, or abdomen area).
Your doctor or nurse will administer the injection for you.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on your response to the medication.
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Romiplostim.
If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
Inform your doctor if you have the following conditions:
- risk factors for developing blood clots e.g. bedridden for a long time, cancer, surgery or trauma, obesity, smoking, contraceptives and hormone replacement therapy
- kidney disease
- liver disease
Let your doctor know if you are pregnant or breastfeeding.
Be sure to check with your doctor or pharmacist before giving Romiplostim to a child or the elderly. Children and elderly people may be more sensitive to the side effects.
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
Routine blood tests may be done before, during, and after your treatment with Romiplostim. Your doctor will advise you about how often you need to have these tests.
Romiplostim may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.
Other side effects include any of the following: headache, nausea, diarrhoea, stomach pain, indigestion, constipation, muscle pain, joint pain, limb pain, numbness or tingling sensation in the hands and feet, tiredness, fever, and difficulty sleeping.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
- unusual bleeding or bruising
- signs and symptoms of allergic reaction e.g. rashes, breathlessness, swelling of the face, eyes, or mouth
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
Avoid alcohol.
Store in the refrigerator, between 2-8°C. Do not allow Romiplostim to freeze. If frozen, this medicine will become ineffective and should not be used.
If needed, this medicine may also be stored at room temperature (up to 25°C) for a single period of up to 30 days.
Protect from light.
Medicines must not be used past the expiry date.
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