Rebif

Rebif Description

interferon beta-1a

Manufacturer:

Merck

Distributor:

Zuellig Pharma
Full Prescribing Info
Description
Each prefilled pen (0.5 ml) contains 22 mcg (6 MIU*) or 44 mcg (12 MIU*) of interferon beta-1a**.
Each cartridge (1.5 ml) contains 66 mcg (18 MIU*) or 132 mcg (36 MIU*) of interferon beta-1a**.
* Million International Units, measured by cytopathic effect (CPE) bioassay against the in-house IFN beta-1a standard which is calibrated against the current international NIH standard (GB-23-902-531).
** produced in Chinese hamster ovary Cells (CHO-K1) by recombinant DNA technology.
Pre-filled pen: with pH 3.5 to 4.5 and osmolarity 250 to 450 mOsm/l.
Cartridge: with pH 3.7 to 4.1 and osmolarity 250 to 450 mOsm/l.
Excipient: 2.5 mg/0.5ml benzyl alcohol.
Excipients/Inactive Ingredients: Mannitol, Poloxamer 188, L-methionine, Benzyl alcohol, Sodium acetate, Acetic acid for pH adjustment, Sodium hydroxide for pH adjustment, Water for injections.
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