Hypersensitivity to ramipril and any other ACE (Angiotensin converting enzyme) inhibitors.
History of angioedema (hereditary, idiopathic or due to previous angioedema with ACE inhibitors or AIIRAs).
Extracorporeal treatments leading to contact of blood with negatively charged surfaces.
Significant bilateral renal artery stenosis or renal artery stenosis in a single functioning kidney.
2nd and 3rd trimester of pregnancy.
Ramipril must not be used in patients with hypotensive or haemodynamically unstable states.