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For males and females: Hypersensitivity to the active substance or any of the excipients; Tumors of the ovary, breast, uterus, testis, pituitary or hypothalamus; Primary gonadal failure.
Additionally for females: Pregnancy; Undiagnosed vaginal bleeding; Ovarian cysts or enlarged ovaries, not related to polycystic ovarian syndrome (PCOS); Malformations of the reproductive organs incompatible with pregnancy; Fibroid tumors of the uterus incompatible with pregnancy.
