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Prelone

Prelone

prednisolone

Manufacturer:

Sunward

Distributor:

Antah Pharma
Concise Prescribing Info
Contents
Prednisolone
Indications/Uses
Primary or secondary adrenocortical insufficiency; rheumatic & hematologic disorders; bronchial asthma; collagen (SLE), dermatologic (pemphigus, severe psoriasis & seborrheic dermatitis), ophth (eye inflammation, herpes zoster ophthalmicus, allergic conjunctivitis), neoplastic (leukemias), GI (ulcerative colitis) diseases; edematous states.
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Dosage/Direction for Use
Initially 5-60 mg daily in divided doses, as single or double dose on alternate days depending on disease.
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Overdosage
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Administration
Should be taken with food.
Contraindications
Hypersensitivity. Systemic fungal infection.
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Special Precautions
CHF, DM, HTN, recent intestinal anastomoses, infectious diseases, myasthenia gravis, ocular herpes simplex; scleroderma renal crisis. Closely observe patients w/ quiescent TB. Prolonged use. Avoid abrupt w/drawal. Concomitant use w/ CYP3A inhibitors. Chronic renal failure. Women of childbearing potential. Pregnancy & lactation. Growth & development of infants & childn. Elderly.
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Adverse Reactions
Fluid & electrolyte disturbance, muscle weakness, osteoporosis, acute pancreatitis, cushingoid state, growth retardation, menstrual irregularities, increased IOP & ICP w/ papilledema, visual disturbances, latent DM manifestations, peptic ulcer w/ possible perforation & hemorrhage, wound healing impairment, convulsion.
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Drug Interactions
Enhanced metabolism by phenytoin, phenobarb, ephedrine & rifampicin; barbiturates. Increased systemic side effects w/ CYP3A inhibitors eg, cobicistat-containing products.
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Storage
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Description
View Prelone description for details of the chemical structure and excipients (inactive components).
Action
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MIMS Class
Corticosteroid Hormones
ATC Classification
H02AB06 - prednisolone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Presentation/Packing
Form
Prelone syr 3 mg/5 mL
Packing/Price
(raspberry flavour) 100 mL x 1's; (raspberry flavour) 120 mL x 1's; (raspberry flavour) 60 mL x 1's
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