Pentoxifylline - oral

Patient Medicine Information
Why do I need this medicine?
Pentoxifylline is used to treat peripheral vascular disease (poor circulation of blood to the arms and legs) and intermittent claudication (cramping muscle pain or numbness in the extremities).
How do I take this medicine?
Take Pentoxifylline exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.

This medicine should be taken with food or immediately after meal. Try to take it at the same time each day.
What should I do if I have forgotten to take this medicine?
Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and return to your normal dosing schedule.

DO NOT double a dose under any circumstances.

If you often forget to take your medicine, let your doctor and pharmacist know.
When should I not use this medicine?
Alert your doctor if you have the following conditions:

- recent stroke
- abnormal bleeding of the blood vessels of the eye
- abnormal heart rhythm
- heart attack
as this medicine may not be suitable for you.
What should I take note of while taking this medicine?
Inform your doctor if you have liver or kidney disease.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly. He may also need to do routine blood tests (e.g. kidney function test, blood clotting test, complete blood count) while you are being treated with Pentoxifylline

Your doctor should also monitor your blood pressure if you are taking medicines for high blood pressure while being treated with this medicine.
What side effects could I experience?
Pentoxifylline may cause dizziness. If affected, do not drive or take part in any activity in which you need to be alert.

Other side effects may include any of the following: nausea, vomiting, stomach disturbance and discomfort and headache.

Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I take this with other medicines?
Inform your doctor if you are taking any of these medicines:

- medicines for pain and inflammation e.g. ketorolac, meloxicam
- medicines for neutralising stomach acid e.g. cimetidine
- medicines for blood clot e.g. warfarin, heparin
- medicines for diabetes e.g. insulin
- theophylline (medicines for asthma)
- ciprofloxacin (antibiotic)

This list does not include all medicines that may interact with Pentoxifylline.

Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
What special dietary instructions should I follow?
Avoid alcohol.
How should I store this medicine?
Store in a cool, dry place away from the reach of children.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on pentoxifylline - oral and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2023 MIMS. All rights reserved. Powered by
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