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Paclitaxel is contraindicated in patients with severe hypersensitivity reactions to paclitaxel, macrogolglycerol ricinoleate (polyoxyl castor oil) or to any of the excipients used in the formulation of Paclitaxel Concentrate for solution for Infusion.
Paclitaxel is contraindicated during lactation.
Paclitaxel should not be used in patients with baseline neutrophils <1.5 x 109/l (<1 x 109/l for KS patients) or platelets <100 x 109/l (<75 x 109/l for KS patients).
In KS, paclitaxel is also contraindicated in patients with concurrent, serious, uncontrolled infections. Patients with severe hepatic impairment must not be treated with paclitaxel.
