Hypersensitivity to the active substance or to any of the excipients listed in Description.
Second and third trimesters of pregnancy (see Precautions and Use in Pregnancy & Lactation).
Biliary obstruction (see Pharmacology: Pharmacokinetics under Actions).
The concomitant use of Olmetec with aliskiren-containing products is contraindicated in patients with diabetes mellitus or renal impairment (GFR <60 mL/min/1.73 m2) (see Interactions and Pharmacology: Pharmacodynamics under Actions).