Discontinue use if gradual or sudden, partial or complete loss of vision or any evidence of ocular changes, onset or aggravation of migraine or development of recurrent, persistent or severe headache, suspicion of thrombosis or infarction, significant rise in BP or if jaundice occurs. Increased risk of CAD in women w/ presence of other predisposing factors eg, smoking, hypercholesterolaemia, obesity, diabetes, history of pre-eclamptic toxaemia & increasing age. Benign & malignant hepatic tumours, hepatic adenoma; thrombosis, embolism or haemorrhage; breast cancer; mood changes, depressive symptoms; epilepsy, history of migraine, cardiac or renal dysfunction; impaired carbohydrate tolerance, depression, gallstones, past history of liver disease, varicose veins, HTN, asthma or any disease prone to worsening during pregnancy eg, multiple sclerosis, porphyria, tetany, otosclerosis. Measure BP, perform breast, abdominal & pelvic exam including cervical cytology. Discontinue at least 4 wk before elective surgery or during prolonged immobilization periods. Contact lens wearers. Not to be taken by patients w/ galactose intolerance, Lapp lactose deficiency or glucose-galactose malabsorption. Not to be used during pregnancy. Lactation.
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