Discontinue use if allergic reactions occur. Hypersensitivity to penicillins, cephalosporins, carbapenems or other β-lactam antibiotics. Not recommended for MRSA infections. Overgrowth of non-susceptible organisms. Pseudomembranous & antibiotic-associated colitis. Monotherapy in critically ill patients w/ known or suspected Pseudomonas aeruginosa
lower resp tract infection. Co-administration w/ potentially nephrotoxic drugs. Monitor transaminase & bilirubin levels in patients w/ hepatic disease. Renal insufficiency. Not to be used during pregnancy & lactation.