Not a causal treatment. Not to be applied on damaged, non-intact skin or mucosal membrane, area of eczema or rash. History of serious GI events & other risk factors associated w/ PUD eg, alcoholism, smoking, corticosteroid therapy; bronchial asthma. May mask signs & symptoms of skin infection. Consider other therapies in chronic disease management eg, OA. Pregnancy & lactation. Low birth wt & newborn infants, infants & toddlers, childn & adolescents. Elderly, debilitated patients.