Lanadelumab is used to prevent attacks of hereditary angioedema (an inherited disorder that causes swelling of the limbs, face, lips, tongue, genitals and airway) in adults, and children aged 12 years and older.
If you or your caregiver had been given the proper training on the preparation and injection techniques of this medicine, you or your caregiver may do the administration.
Lanadelumab is to be injected subcutaneously (into the fatty layer under the skin, usually in the thigh, upper arm or abdomen area).
Use Lanadelumab exactly as directed by your doctor or according to the instructions on the label. Do not use more or less than instructed by your doctor.
This medicine is available as a single-use vial or as a pre-filled syringe. Make sure you know how to use the specific device you have been given. If you have problems or do not understand the instructions, ask your doctor or pharmacist.
Remember to rotate the injection sites. Do not inject into the same area all the time. New injection sites should be at least 1.5 inches away from the previous injection site. Do not inject near the navel (belly button).
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the course of your treatment depending on your condition and response to the medication.
Lanadelumab must be administered regularly for it to be effective. Continue using this medicine even when you feel better. Do not stop using it unless instructed by the doctor.
Inject the missed dose as soon as you remember, but there must be at least 10 days between each dose.
DO NOT double a dose under any circumstances.
Inform your doctor or pharmacist immediately if you forgot to administer your dose.
Do not use Lanadelumab if you ever had an allergic reaction (e.g. rashes, breathlessness, swollen eyes) to this medicine or any of its ingredients.
Let your doctor know if you are pregnant or breastfeeding.
Be sure to check with your doctor or pharmacist before giving Lanadelumab to a child. Children may be more sensitive to the side effects.
If you are going for certain laboratory tests (e.g. blood test known as activated partial thromboplastin time [aPTT]), inform your doctor that you are using this medicine.
Why is it important to keep my appointments with the doctor?
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
- Routine tests (e.g. liver function) may be done while you are being treated with Lanadelumab. Your doctor will advise you about how often you need to have these tests.
- Regular monitoring of signs and symptoms of allergic reactions may also be needed.
Lanadelumab may cause any of the following side effects: headache, diarrhoea, dizziness, muscle pain, rash, and pain, swelling, itching or bruising at the injection site.
If you develop rashes, breathlessness, swollen mouth or eyes, stop using Lanadelumab and inform your doctor immediately. These could be signs of an allergic reaction.
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements and medicines that you buy without a prescription.
Avoid alcohol.
Store in the refrigerator, between 2-8°C. Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used.
Protect from light. Do not shake.
If you notice that the injection has changed colour or has become cloudy, do not use it. Throw it away and use a new injection.
Medicines must not be used past the expiry date.
Available products of Lanadelumab may vary with their storage requirements. Ask your doctor or pharmacist on how to properly store this medicine.
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