Finerenone is used to lower the risk of worsening kidney problems, heart attack, and hospitalisation for heart failure in individuals with long-term kidney disease associated with type 2 diabetes (a long-term condition in which the body gradually becomes resistant to the effects of insulin, or the pancreas does not produce enough insulin).
Take Finerenone exactly as directed by your doctor or according to the instructions on the label. Do not take more or less than instructed by your doctor.
You may take this medicine with or without food. Swallow the tablet whole with a glass of water. If you have difficulty swallowing the tablet, you may crush the tablet and mix it with water or soft foods, such as applesauce. Stir and consume the mixture immediately. Try to take it at the same time each day.
The dose of this medicine will be decided by your doctor. Your doctor will advise you on the treatment timeframe depending on the severity of your condition.
Finerenone must be taken regularly for it to be effective. Continue taking this medicine even when you feel better. Do not stop taking it unless instructed by the doctor.
Take the missed dose as soon as you remember on the same day you missed the dose. If you miss a day, skip the missed dose and return to your normal dosing schedule.
DO NOT double a dose under any circumstances.
If you often forget to take your medicine, let your doctor and pharmacist know.
Alert your doctor if you have adrenal insufficiency (a rare disorder where the adrenal glands produce insufficient amounts of certain hormones) as Finerenone may not be suitable for you.
Do not take Finerenone with certain medicines to treat fungal infection, HIV infection, depression, and certain antibiotics. Please see the section "Can I take this with other medicines?" below for more information.
Inform your doctor if you have the following conditions:
- currently have or have had high potassium levels in the blood
- moderate or severe liver disease
Let your doctor know if you are pregnant or planning to get pregnant.
It is important that you do not get pregnant while being treated with this medicine. You must use proven birth control methods during Finerenone therapy. You may wish to discuss birth control methods with your doctor or pharmacist.
Inform your doctor if you are breastfeeding. Your doctor may advise you to avoid breastfeeding while taking this medicine and for 1 day after stopping the treatment.
Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
Routine tests (e.g. kidney and liver function, potassium levels in the blood) may be done while you are being treated with this medicine. Your doctor will advise you about how often you need to have these tests.
Finerenone may cause any of the following side effects: itching, nausea, tiredness, headache, confusion, and dizziness or lightheadedness.
Some side effects may need immediate medical help. Alert your doctor quickly if you experience muscle weakness, cramping or numbness, and fast or irregular heartbeat.
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Do not take Finerenone if you are taking any of these medicines:
- certain medicines to treat fungal infection e.g. ketoconazole, itraconazole
- certain antibiotics e.g. clarithromycin, telithromycin
- certain medicines for HIV infection e.g. ritonavir, nelfinavir, cobicistat
- nefazodone (medicine to treat depression)
Inform your doctor and pharmacist if you are taking any of these medicines:
- water pills or medicines for water retention e.g. amiloride, triamterene
- certain medicines for high blood pressure e.g. eplerenone
- other antibiotics e.g. erythromycin, trimethoprim or trimethoprim + sulfamethoxazole combination
- medicines for epilepsy (fits or seizures) e.g. carbamazepine, phenytoin, phenobarbital
- efavirenz (medicine for HIV infection)
- rifampicin (medicine to treat TB [an infection known as tuberculosis])
- potassium supplements
- St. John's wort (herbal medicine)
This list does not include all medicines that may interact with Finerenone.
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
Avoid alcohol.
Avoid excessive consumption of grapefruit or grapefruit juice (more than 1 litre a day).
Store in a cool, dry place away from the reach of children.
Medicines must not be used past the expiry date.
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