Symptoms: Somnolence, agitation, aggression, depressed level of consciousness; respiratory depression and coma were observed with levetiracetam overdoses.
Management of Overdose: There is no specific antidote for levetiracetam. Treatment of an overdose will be symptomatic and may include haemodialysis. The dialyser extraction efficiency is 60% for levetiracetam and 74% for the primary metabolite.