Hypersensitivity. Known or suspected breast or genital tract cancer; active or history of arterial or VTE or severe thrombophlebitis; porphyria; undiagnosed vag bleeding. Severe hepatic dysfunction or disease. Known missed abortion or ectopic pregnancy.
Discontinue use if MI, cerebrovascular disorders, arterial or VTE (VTE or pulmonary embolism), thrombophlebitis or retinal thrombosis are suspected; transient ischemic events, appearance of sudden severe headaches or papillary edema- or retinal hemorrhage-related vision impairments occur. History of depression. Epilepsy, migraine, asthma, cardiac dysfunction. Diabetic patients; patients >35 yr, smokers, w/ risk factors for atherosclerosis. Assess infertility causes prior to treatment. Avoid abrupt discontinuation. May affect ability to drive & use machines. Renal & mild to moderate hepatic dysfunction. 2nd & 3rd trimesters of pregnancy. Not to be used during lactation.
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