This medicinal product is contraindicated in cases of: Hypersensitivity to gliclazide, or to any of the excipients listed in Description, other sulphonylureas or sulphamides, Type 1 diabetes, Diabetic pre-coma and coma, diabetic keto-acidosis, Severe hepatic or renal insufficiency: In these cases, the use of insulin is recommended, Treatment with miconazole (see Interactions), Lactation (see Use in Pregnancy & Lactation).