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Pregnancy: Safety for use of calcipotriol during human pregnancy has not been established. When calcipotriol was administered orally in animals, reproductive toxicity has been shown. Calcipotriol should not be used during pregnancy unless clearly necessary.
Breast-feeding: It is unknown whether calcipotriol is excreted in human milk. Caution should be exercised when prescribing Daivonex ointment to women who breast-feed. The patient should be instructed not to use Daivonex ointment on the breast when breast-feeding.
Fertility: Studies in rats with oral doses of calcipotriol demonstrated no impairment of male and female fertility.
