Cetrotide

Cetrotide

cetrorelix

Manufacturer:

Merck

Distributor:

Zuellig Pharma
Concise Prescribing Info
Contents
Cetrorelix acetate
Indications/Uses
Prevention of premature ovulation in patients undergoing controlled ovarian stimulation followed by oocyte pick-up & assisted reproductive techniques.
Dosage/Direction for Use
SC Administer once daily into lower abdominal wall at 24-hr intervals, either morning or evening. Administration in the morning: Commence on day 5 or 6 of ovarian stimulation (approx 96-120 hr after start of ovarian stimulation) w/ urinary or recombinant gonadotropins. Continue throughout gonadotropin treatment period including day of ovulation induction. Administration in the evening: Commence on day 5 of ovarian stimulation (approx 96-108 hr after start of ovarian stimulation) w/ urinary or recombinant gonadotropins. Continue throughout gonadotropin treatment period until the evening prior to day of ovulation induction.
Contraindications
Hypersensitivity to cetrorelix acetate or any structural analogues of gonadotropin-releasing hormones, extrinsic peptide hormones. Severe renal impairment. Pregnancy & lactation.
Special Precautions
Not to be used in women w/ allergic condition or known history of allergic predisposition. Mild to moderate ovarian hyperstimulation syndrome (OHSS). Administration during repeated ovarian stimulation procedure. Hepatic & renal impairment. Not to be used during pregnancy & lactation. Congenital anomalies.
Adverse Reactions
Mild to moderate OHSS; local inj site reactions eg, erythema, swelling, pruritus.
MIMS Class
Trophic Hormones & Related Synthetic Drugs
ATC Classification
H01CC02 - cetrorelix ; Belongs to the class of anti-gonadotropin-releasing hormones. Used in hypothalamic hormone preparations.
Presentation/Packing
Form
Cetrotide powd for inj 0.25 mg
Packing/Price
7 × 1's
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