Brolucizumab - intravitreal

Patient Medicine Information
Why do I need this medicine?
Brolucizumab is used to treat neovascular (wet) age-related macular degeneration (an eye disorder wherein abnormal blood vessels form and grow at the back of the eye, causing decreased vision).
How do I use this medicine?
Brolucizumab is to be given by intravitreal injection (into the space in the back of the eye called the vitreous cavity).

Your eye doctor will administer the injection for you. Your doctor will also give you anaesthesia to prevent any pain from the injection.
What should I do if I have forgotten to use this medicine?
Ensure that you keep all appointments with your doctor so that you do not miss any doses. Your doctor also needs to regularly monitor your response to Brolucizumab.

If you miss an appointment or miss an injection, alert your doctor or nurse. A replacement appointment or injection should be given as soon as possible.
When should I not use this medicine?
Alert your doctor if you have the following conditions:
  • eye infections
  • eye inflammation
as Brolucizumab may not be suitable for you.
What should I take note of while using this medicine?
Inform your doctor if you have the following conditions:
  • glaucoma (increased pressure in the eye)
  • damage in retina (part of the eye)
  • history of stroke or heart attack within the last 3 months
  • history of eye inflammation and/or retinal vascular occlusion (blockage of a vein in the back of the eye) in the last 12 months
Be sure to check with your doctor or pharmacist before using Brolucizumab. Women and individuals of Japanese ancestry may be more sensitive to the side effects.

Keep your appointments with your doctor. Your doctor needs to monitor your condition and check your response to the medication regularly.
  • Eye examinations may be done after each injection to check if there is an increase in pressure inside the eye.
  • Regular monitoring of changes in vision may also be needed.
What side effects could I experience?
Brolucizumab may cause temporary problems with your eyesight. Always keep your doctor updated on any changes in your eyesight. If you cannot see clearly, avoid driving and any activity in which you need to see clearly.

Other side effects include any of the following: eye pain, eye irritation, eye inflammation, and rashes.

Some side effects may need immediate medical help. Alert your doctor quickly if you experience any of the following:
  • sudden change in vision, blurred or decreased vision
  • excessive pain or discomfort in your eye, worsening eye redness
  • increased pressure in the eye
  • increased sensitivity to light
  • sudden appearance of many dark floating spots, seeing flashes of lights
  • sudden difficulty in speaking, weakness or numbness in the face, arms or legs
  • sudden sharp chest pain
Inform your doctor if any of these side effects do not go away or are severe, or if you experience other side effects.
Can I use this with other medicines?
Always notify your doctor and pharmacist if you are taking any other medicines, including herbal tonics such as traditional Chinese medicines, supplements, and medicines that you buy without a prescription.
How should I store this medicine?
Store in the refrigerator, between 2-8°C. Do not allow to freeze. If frozen, this medicine will become ineffective and should not be used. Protect from light.

May store unopened vial or pre-filled syringe below 25°C for up to 24 hours before use.

Medicines must not be used past the expiry date.
This information is independently developed by MIMS based on brolucizumab - intravitreal and is provided for your reference only. It is not a replacement for and should only be used in conjunction with full consultation with a licensed healthcare professional, the information provided by your pharmacist and/or the manufacturer of the medication. It may not contain all the available information you require and cannot substitute professional medical care, nor does it take into account all individual circumstances. Although great effort has been made to ensure content accuracy, we shall not be held responsible or liable for any claims or damages arising from the use or misuse of the information contained herein, its contents or omissions, or otherwise. Copyright © 2023 MIMS. All rights reserved. Powered by
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