BIOCOXIB 90 MG and 120 MG Film Coated Tablet contraindicated in: Patients with known hypersensitivity to any component of this product.
Patients with active peptic ulceration or active gastrointestinal (GI) bleeding.
Patients who after taking acetylsalicylic acid or NSAIDs including COX-2 (cyclooxygenase-2) inhibitors, experience bronchospasm, acute rhinitis, nasal polyps, angioneurotic oedema, urticaria, or allergic-type reactions.
Pregnancy and lactation.
Patients with severe hepatic dysfunction (serum albumin <25 g/l or Child-Pugh score ≥10).
Patients with estimated renal creatinine clearance <30 ml/min.
Children and adolescents under 16 years of age.
Patients with inflammatory bowel disease.
Patients with congestive heart failure (NYHA II-IV).
Patients with established ischaemic heart disease, peripheral arterial disease, and/or cerebrovascular disease.
Patients who have increased risk of cardiovascular disease (ischaemic heart disease and stroke).
Patients with hypertension (high blood pressure) whose blood pressure is not under control.