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For oral administration.
This is slow release tablet. It should be swallowed whole with liquid, and must not be divided or chewed. The recommended initial daily dosage is 100mg. As a general recommendation, the dose should be individually adjusted. Adverse effects may be minimized by using the lowest effective dose for the shortest duration necessary to control symptoms (see PRECAUTIONS).
Established cardiovascular disease or significant cardiovascular risk factors: Treatment with diclofenac is generally with established cardiovascular disease (congestive heart failure, established ischemic heart disease, peripheral arterial disease) or uncontrolled hypertension. If needed, patients with established cardiovascular disease, uncontrolled hypertension, or significant risk factors for cardiovascular disease (e.g. hypertension, hyperlipidaemia, diabetes melilitus and smoking) should be treated with diclofenac only after careful consideration and only at doses ≥ 100 mg daily if treated for more than 4 weeks (see PRECAUTIONS).
