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Aurasert should not be used concomitantly to patients taking monoamine oxidase inhibitors, while switching from a MAOI to sertraline or vice-versa, a washout period of at least 14 days should elapse.
Aurasert is also contraindicated in patients with a previous history of hypersensitivity to sertraline.
Mutagenicity/carcinogenicity: Sertraline has no genotoxic effects with or without metabolic activation. Possibility of increase in follicular adenomas of the thyroid, unaccompanied by thyroid hyperplasia is higher if the dose exceeds 40mg/kg.
