Amnoz Dosage & Drug Information

Concise Prescribing Info Full Prescribing Info Contents Description Action Indications/Uses Dosage/Direction for Use Overdosage Contraindications Special Precautions Use In Pregnancy & Lactation Adverse Reactions Drug Interactions Storage MIMS Class ATC Classification Regulatory Classification Presentation/Packing

Concise Prescribing Info

Contents

Amlodipine

Indications/Uses

1st-line treatment of HTN, myocardial ischemia whether due to fixed obstruction (stable angina) &/or vasospasm/vasoconstriction (Prinzmetal's or variant angina) of coronary vasculature.

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Dosage/Direction for Use

Initially 5 mg once daily, may be increased to max: 10 mg.

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Overdosage

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Administration

May be taken with or without food: Swallow whole w/ water.

Contraindications

Hypersensitivity to amlodipine or dihydropyridines.

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Special Precautions

CHF. May affect ability to drive & use machines. Hepatic impairment. Pregnancy & lactation. Childn.

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Use In Pregnancy & Lactation

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Adverse Reactions

Headache, dizziness, somnolence; palpitations; flushing; abdominal pain, nausea; edema, fatigue.

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Drug Interactions

Increased BP-lowering effects w/ grapefruit or grapefruit juice. Increased exposure to simvastatin. Increased risk of hypotension w/ strong or moderate CYP3A4 inhibitors eg, PIs, azole antifungals, macrolides (ie, erythromycin, clarithromycin), verapamil, diltiazem. Varied plasma conc w/ strong CYP3A4 inducers eg, rifampicin, Hypericum perforatum. Increased tacrolimus blood levels. Increased trough conc of cyclosporin.

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Storage

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Description

View Amnoz description for details of the chemical structure and excipients (inactive components).

Action

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MIMS Class

Calcium Antagonists / Anti-Anginal Drugs

ATC Classification

C08CA01 - amlodipine ; Belongs to the class of dihydropyridine derivative selective calcium-channel blockers with mainly vascular effects. Used in the treatment of cardiovascular diseases.

Regulatory Classification

Presentation/Packing

Form

Amnoz tab 10 mg

Packing/Price

10 × 10's

Form

Amnoz tab 5 mg

Packing/Price

10 × 10's

Amnoz

amlodipine

Manufacturer:

Pharmaniaga Manufacturing Berhad

Distributor:

Pharmaniaga Logistics