Zyloric

Generic Name : Allopurinol

Indication : Idiopathic gout, uric acid lithiasis, acute uric acid nephropathy; neoplastic & myeloproliferative disease w/ high cell turnover rates in which high urate levels occur either spontaneously or afte...

Manufacturer : GlaxoSmithKline Indonesia

MIMS Class : Hyperuricemia & Gout Preparations

Allopurinol

Mechanism of Action

Description:
Mechanism of Action: Allopurinol is a structural analogue of hypoxanthine that acts on purine catabolism without disrupting the biosynthesis of vital purines. It inhibits xanthine oxidase, the enzy...

Zyloric Drug Interactions

Prolonged activity of 6-mercatopurine or azathioprine. Increases plasma t_½ of vidarabine. Decreased effect by uricosurics eg, probenecid & large doses of salicylates. Increased r...

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