MRSA & VRE of the following infection caused by gm +ve bacteria: Nosocomial pneumonia; complicated skin & soft tissue infections including diabetic foot infections w/o concomitant osteomyelitis caused by S. aureus, S. pyogenes or S. agalactiae.
AdultNosocomial pneumonia, complicated skin & soft tissue infections 600 mg IV or PO 12 hrly for 10-14 days. Paed (6-11 yr) 10 mg/kg IV or PO 8 hrly for 10-14 days. Adult Infection due to MRSA 600 mg 12 hrly.
Monitor platelet counts for patients w/ preexisting myelosuppression (including anemia, leucopenia, pancytopenia & thrombocytopenia), increased risk of bleeding, receiving concomitant medications that may decrease platelet count of linezolid for >2 wk. Visual function should be monitored (extended period). Lactic acidosis, serotonin syndrome. Pregnancy & lactation.
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