Oropharyngeal, oesophageal or vulvovaginal candidiasis & serious systemic candidal infection. Meningitis caused by Cryptococcus neoformans.
Dosage/Direction for Use
Oropharyngeal candidiasisAdult 50 mg once daily for 1-2 wk. Oesophageal candidiasis 50 mg once daily for 14-30 days. Vulvovag candidiasisAdult 150 mg as a single dose. Systemic candidiasisAdult 1st day: 400 mg as single dose then 200 mg once daily for 4 wk & 2 wk following resolution of symptom. Cryptococcal meningitisAdult 1st day: 400 mg as a single dose then 200-400 mg once daily for 10-12 wk after CSF is sterile. Suppression of relapse in patients w/ AIDS Maintenance: 200 mg once daily.
Administration
May be taken with or without food.
Special Precautions
Discontinue therapy if liver disease develop. Alternative antifungal therapy may be required in patients w/ overgrowth of nonsusceptible strains of candida. Pregnancy. Childn <16 yr.
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