Skin & soft tissue infections due to non-penicillinase-producing Staph, Streptococcus spp, E. coli. Resp tract infection due to H. influenzae, Streptococcus, S. pneumoniae, non-penicillinase-producing Staph, E. coli. GUT infection due to E. coli, P. mirabilis, S. faecalis. Gonorrhea due to N. gonorrheae.
Dosage/Direction for Use
Adult & childn >20 kg 250-500 mg 8 hrly. Childn <20 kg 20-40 mg/kg daily in divided doses 8 hrly. Patients under peritoneal dialysis Max dose: 500 mg daily. Gonococcal urethritis 3 g as a single dose.
Administration
May be taken with or without food: May be taken w/ meals for better absorption & to reduce GI discomfort.
Contraindications
Hypersensitivity to β-lactam antibiotics ie, penicillins, cephalosporins.
Special Precautions
Not for treatment of meningitis or bone & joint infections. Patients w/ lymphatic leukemia. May cause severe colitis. Perform kidney, liver function & blood test during prolonged therapy. Patients w/ kidney failure. Pregnancy, lactation.
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