Vomitas Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Domperidone

Indications/Uses

Acute nausea & vomiting. Nausea & vomiting due to levodopa & bromocriptine treatment lasting >12 wk. Short-term therapy of functional dyspepsia, nausea & vomiting due to chemo- or radiotherapy in childn.

Dosage/Direction for Use

Functional dyspepsia Adult 10-20 mg 3 times daily & at night. Max duration of treatment: 12 wk. Nausea & vomiting (including those caused by levodopa & bromocriptine) Adult & elderly 10-20 mg every 4-8 hr. Nausea & vomiting due to chemo- or radiotherapy Childn 0.2-0.4 mg/kg/day at 4-8 hr intervals.

Administration

Should be taken on an empty stomach: Take 15-30 min before meals.

Contraindications

Prolactinoma. Whenever stimulation of GI motility might be dangerous. Intolerance to domperidone.

Special Precautions

Long-term treatment. Hepatic or renal dysfunction. Pregnancy & lactation. Infant <1 yr.

Adverse Reactions

Rarely, sedation, extrapyramidal reactions, galactorrhea, gynecomastia, dry mouth, headache, diarrhea, rash, thirst, anxiety, itch. May induce plasma prolactin level.

View ADR Monitoring Form

Drug Interactions

Action inhibited by antimuscarinic agents & opioid analgesics. Decreases the effect of bromocriptine. Decreased bioavailability w/ antacids.

MIMS Class

GIT Regulators, Antiflatulents & Anti-Inflammatories

ATC Classification

A03FA03 - domperidone ; Belongs to the class of propulsives. Used in the treatment of functional gastrointestinal disorders.

Regulatory Classification

Presentation/Packing

Form

Vomitas fast disintegrating tab 10 mg

Packing/Price

5 × 10's (Rp194,250/boks)

Form

Vomitas syr 5 mg/5 mL

Packing/Price

(strawberry flavor) 60 mL x 1's (Rp42,000/botol)

Vomitas

domperidone

Manufacturer:

Kalbe Farma