Tiaryt Dosage & Drug Information

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Concise Prescribing Info

Contents

Amiodarone HCl

Indications/Uses

Suppression & prevention of life-threatening ventricular & supraventricular arrhythmias, paroxysmal atrial fibrillation, atrial flutter, ectopic atrial tachycardia.

Dosage/Direction for Use

Ventricular arrhythmia Initially 800-1,600 mg daily for 1-3 wk. Supraventricular arrhythmia 600 mg daily in divided doses for 1 wk, thereafter 200-400 mg daily.

Administration

May be taken with or without food: Take consistently w/ or w/o meals. Take w/ meals if high dose or to reduce GI discomfort.

Contraindications

Severe sinus node dysfunction, 2nd- & 3rd-degree AV block, syncope. Thyroid dysfunction, iodine sensitivity. Pregnancy & lactation.

Special Precautions

Monitor BP, liver function & thyroid function regularly.

Adverse Reactions

Corneal microdeposits, photosensitization & pigmentation; hyperthyroidism; pulmonary toxicity & neurotoxicity; GI irritation may occur.

View ADR Monitoring Form

Drug Interactions

Increased risk of ventricular arrhythmias w/ TCA, astemizole, terfenadine & phenothiazines. Enhances anticoagulant effects of warfarin. Inhibits metabolism of phenytoin. Increased risk of bradycardia, AV block & myocardial depression w/ β-blockers, diltiazem & verapamil. Increases plasma conc of digoxin. Toxicity increased if hypokalemia occurs w/ loop diuretics & thiazides. Cimetidine increase plasma conc.

MIMS Class

Cardiac Drugs

ATC Classification

C01BD01 - amiodarone ; Belongs to class III antiarrhythmics.

Regulatory Classification

Presentation/Packing

Form

Tiaryt tab 200 mg

Packing/Price

5 × 6's (Rp114,000/boks)

Tiaryt

amiodarone

Manufacturer:

Fahrenheit