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The dose should be adjusted in patients with impaired renal function.
It should be used in pregnant and nursing women only if clearly needed.
Safety and effectiveness of drug in children aged less than 6 months old have not been established.
It should be given with caution to penicillin-sensitive patients.
It should be carefully administered to patients with a personal or familial history of some forms of allergies such as bronchial asthma, rash or urticaria.
It should be carefully administered to patients with nutrition deficiency, patients receiving parenteral nutrition, elderly patients or patients in a debilitated state.
It should be used with caution in patients with a history of gastrointestinal disease, particularly colitis.
Prolonged treatment may result in overgrowth of resistant organisms. If superinfection occurs, treatment should be discontinued.
