Simpenem Dosage & Drug Information

Concise Prescribing Info Bahasa Concise Prescribing Info

Concise Prescribing Info

Contents

Meropenem trihydrate

Indications/Uses

Pneumonia, nosocomial pneumonia, UTI, intra-abdominal infections, gynecological infections, skin & skin structure infections, meningitis, septicemia in adult & childn. Empiric treatment in adult w/ infection suspected w/ febrile neutropenia.

Dosage/Direction for Use

IV Adult Pneumonia, UTI, gynecological infections eg, endometritis, skin & skin structure infections 500 mg 8 hrly. Nosocomial pneumonia, peritonitis, suspected neutropenia, septicemia 1 g 8 hrly. Meningitis 2 g 8 hrly. Childn 3 mth-12 yr 10-20 mg/kg 8 hrly. Meningitis 40 mg/kg 8 hrly. Childn >50 kg Adult dose.

Contraindications

Hypersensitivity reactions.

Special Precautions

History of hypersensitivity to β-lactam antibiotics. History of allergy. Not recommended for infections due to MRSA. Patients w/ liver disease. Pregnancy & lactation. Not recommended for babies <3 mth.

Adverse Reactions

Local inj site reactions, systemic allergic reactions, rash, pruritus, urticaria, erythema multiform, SJS, TEN, abdominal pain, nausea, vomiting, diarrhea, pseudomembranous colitis, reversible thrombocytopenia, eosinophilia, thrombocytopenia, leucopenia, neutropenia, +ve results of Coomb's test, increased serum bilirubin, transaminase, alkaline phosphatase & LDH, headache, paresthesia, convulsion, oral & vag candidiasis.

View ADR Monitoring Form

Drug Interactions

Probenecid.

MIMS Class

Other Beta-Lactams

ATC Classification

J01DH02 - meropenem ; Belongs to the class of carbapenems. Used in the systemic treatment of infections.

Regulatory Classification

Presentation/Packing

Form

Simpenem powd for inj 1 g

Packing/Price

1's (Rp450,000/vial)

Simpenem

meropenem

Manufacturer:

Simex