Adult & childn >12 yr 1 g 12 hrly, may be increased to 2 g twice daily in serious infection. Infant & childn 1 mth-12 yr (>50 kg) Adult dose (max: 12 g daily), <50 kg 50-180 mg/kg daily IM/IV in 4-6 divided doses. Neonate 1-4 wk 50 mg/kg IV 8 hrly, 0-1 wk 50 mg/kg IV 12 hrly. Uncomplicated infections 1 g 12 hrly IM/IV. Max: 2 g daily. Moderate to serious infections 1-2 g 8 hrly IM/IV. Max: 3-6 g daily. Infections requiring higher dose 2 g 6-8 hrly IV. Max: 6-8 g daily. Life-threatening infections 2 g 4 hrly IV. Max: Up to 12 g daily. Uncomplicated gonorrhoea 1 g IM. Peri & post-op 1-2 g 30-60 min prior to surgery.
Contraindications
Hypersensitivity.
Special Precautions
May cause colitis in patients w/ history of GI diseases. May cause cross sensitivity in patients w/ hypersensitivity to penicillin. Pregnancy especially on 3rd trimester. Lactation.
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